Sorry, I couldn’t help myself with that title. On to the update.

We sent away for some genetic testing at to find out which specific genetic mutations (if any) and SNP’s (Single Nucleotide Polymorphism) little man had. We had suspected he most likely did have a mutation, and given what we had researched, we thought there was a high probability it was MTHFR. But, we were WRONG!

He did not, in fact, have MTHFR, however he did have a mutation called MAO-A. This particular genetic mutation is often referred to as the “warrior gene” as those who carry it can display a propensity towards…wait for it…aggressive behaviors! Ding, ding, ding! We have a winner! Or should I say, warrior?

Little man’s particular mutation (TT alleles of 2R) means that he has very low production of MAO-A. MAO-A is an enzyme which metabolizes serotonin, norepinephrine, and histamine. Essentially, with such low levels of MAO-A, he isn’t able to convert these things. What that leads to is increased seratonin, which doesn’t allow for oxytocin production. Oxytocin is often known as the “bonding” hormone, and when someone isn’t producing enough oxytocin, you can imagine why they might feel angry or act in an aggressive manner.

Here are two interesting links if you would like to learn more:

About the MAO-A Gene

The MAO-A and Autism Spectrum Disorder Connection (And I would be willing to expand this to include nearly all autoimmune disorders and many neuropsychiatric disorders…especially in boys)

Conventional treatment would have us use progesterone to combat his low MAO-A production. But, as you know if you’ve read any other article in this blog, we aren’t very conventional.

To be continued after further research…

Hugs and Healing,

Mama Bear